SBIR/STTR Matching Grant


HSSA will invest in innovative research by small businesses to expedite commercialization and spur job growth.

Amount & Timeframe

  • Total of up to $500,000 over the course of the grant
  • Open grant (applicants may apply at any time)


  • Pre-proposal letter of intent (LOI) required
  • Full, written proposal, if requested
  • Must have documented matching SBIR/STTR Phase 1 or 2 grants, or other foundation grants that are “proof-of-concept”
  • Requires agreement with conditions of HSSA’s Grant Award Agreement

Grant Application Process

HSSA requires all applicants for health sciences research must first provide a Letter of Intent (LOI).

You must verify that you meet the HSSA criteria for a specific grant category selected. You may do that here by responding to the following requests.

HSSA will then notify the applicant whether or not to submit a full Grant Application. HSSA will provide applicant a link to the on-line formal Grant Application.

The Applicant must provide a full copy of the approved grant for which a matching HSSA grant is being requested.

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